Bio-Minicry: Next Phase of Sustainable Imitating Technology

Bio-Minicry: Next Phase of Sustainable Imitating Technology BIO-MIMICRY: THE NEXT PHASE OF MODERN SUSTAINABLE IMITATING TECHNOLOGY Abstract: Bio mimicry is a form of learning and then reproduce natures forms, processes, and ecosystems to create more sustainable designs. Bio mimicry has stepped into the Advanced technologies section when it comes to thinking out of the box strategies; which mainly relate to adapt the behaviour and environmental characteristics of nature or the living species including mammals, reptiles, flaura and fauna. This review article submits the overview of the technology of the world around us by adapting the blueprints from nature, and applying those ideas to improve the co-existed ones. The Review tries to emphasise on the various economical and ecological aspects of the current Bio mimic technology in various fields scaling down their Growth and Cons in Production, Evaluative thinking and Green Technology. Introduction: Bio-mimicry mimicking Natures designs to overcome the manmade designed challenges which can be applied to a varied range of obstacles all the way from drafting a CAD model to several systems, services and the environmental aspects of the product development. Bio-Mimicry has been along from a long time since the 1900s when the revival of the pollen grains of the plant cocklebur got stuck to his coat which empowered Swiss engineer Georges de Mestral to invent a new type of fastener which later became famous and patented as Velcro Industries. This incident embarked a new process and methodology of thinking for new discoveries and inventions. The Method to imitate the behaviour the organisms or the horticulture is mainly according to the type of imitation shelled down for a particular application which is mainly divided into: (1) Bio inspiration (2) Bio replication (3) Bio imitation. The other area of concern for todays technological ladder is to produce eco friendly and much more Green designs and products which can adhere to the current eco system regarding the concept of Form follows Function . Bio mimicry can be stated as the example of a Helicopter being as similar as a bumble bee but the mechanism of hovering are totally different, which states that only a part of the idea or concept has been adapted to make something to travel at very high grade speeds. The Lotus plant has the ability to repel the water droplets on its surface which created avenue for a new technological impact for the surface coats and paint industries enabling them to make paints which could swipe off the dirt from the surface without any external cleaning agents. Medical field has also advanced from the natures geometry in such a manner that it can now adapt the soul DNA structures of various Microorganisms to tackle the cancer agents along with widely induced drug delivery system and Organs on chips concept which is indeed revolutionary. The manufacturing scale and the designs are also mimicked from the nature: the sustainability concept along with the proficient use to the application, such as surface coat for anti corrosive metals and several solar cells also use the mimicked concept of bug eyes being anti-reflective and adapting the UV rays band spectrum at a much higher scale than the normal solar cells imparting higher efficiencies to the solar cell output. The main agenda is to invent production, operations, and methodologies that are well-adhered to a sustainable Green Living. The core idea is that nature has already solved many of the problems we are grappling with. Animals, plants, and microbes are the consummate engineers. After billions of years of research and development, failures are fossils, and what surrounds us is the secret to survival. Why bio mimicry is the new face of advancement in 21st century science? Todays world is facing the hurdles of overcoming the defects from their products and trying to maintain them for a longer run for much better output both economic and ecological aspects. The constant graph of growth for the awareness of bio mimicry embarks the start of a phase, all the way from the industrial model to an ecological one. Experts suggest that the industrial revolution period may have admired us with some of the many vital innovations, but it was on the base of ecological depletion and non sustainable production technology. The following review paper will cover all the fields that have been developing their scaled growth over the past decade gradually sparking the innovations and replicating natures system and its operations in their respective field for much better output that theyd usually get without using them. The recent developments in nanotechnology and manufacturing are helping us to manipulate and innovate products more like Nature does from the bottom up method, but there is still much of the gap to fill such as producing materials at ambient temperatures and still have desired properties, such as strength without wasting any energy. The Flowchart resembles the fact that a method or a process has been adapted now by the recent innovators and Big MNSCS regarding the fact to make or produce something new everytime in the research and development section. The industries are much more imparting importance to their RD department today because of the constant demand for better products with high grade efficiencies and higher production rates. They also have the criteria to waste minimal of the raw products used in the production which is inevitable at the present scale technology. Bio mimicry steps in there with the concept of giving out the agendas for production areas to work and emphasise about making and designing Green products which would be suitable to the environment as well as the application by adapting different concepts and ideas from nature. The Eco Friendly method is generally based on three factors Economic, Environmental and Social Aspects. The Main goal is to achieve the complete interaction and balance co relating in all these three factors.Adding to that the production and the blueprints of a company always have the environmental indicators which are Carbon Footprint, Energy Consumption, Air acidification and Water Eut rophication. Nanofabrication has a greater role to play in the field of bio mimicry because of the sole reason to scale grade and study the roots formation of a structure and mimicking it to a real scale model application. Example: Studying the gecko feet structure from the DNA scale level to understand the physics and the arrangement of the surface involved in high quality of friction imparting that theme to that of the tyres i.e. real scale model application. The Following subtopics of this review covers various applications where the symphony of nanofabrication and bio mimicry is synched to produce application of high intellectual usage for the industry as well as day to day science ; their approach, their limitations, advantages and problems that they have to tackle have been reviewed and discussed thoroughly. The Classification of Bio Mimicry Applications flowchart: Medicine:Nanofabrication technology has enabled the scientists and researchers all over the globe to widen their horizon to an extent where they can create cell structures that go beyond the current three dimensional in vitro models by giving them a new formed tissue tissue interfaces, spatiotemporal chemicals and dynamic mechanisms and behaviour of the micro organisms. In One research the living cells are structured within the microfluidic aids that have been designed to withstand and keep the tissues intact in the same manner as they are placed in the microorganisms. Adding to that also the organ to organ behaviour is observed and analysed so as to know the interaction between a kidney tissue and a liver tissue with their co relation to the brain cells. This study requires pathophsyciology which can be helped to understand how Organs on chip can behave when they are tested in field. PDMS a microdevice containing poly-dimethylsiloxane are molded inversely that mimics the complex structure of the relative tissue epithelial interface so as to know their behaviour in the body. Various body organs such as Lungs, kidney, liver, Breasts Chips have been formed and tested mainly on animals which proves to be quite costly and dreadful. Another application is to replicate the morphology of the chemotoxins from the cancer cells during their treatment to ease the process and the fight against the same known as sink cells which scavenge the chemokins. The embarkment of mimicking the mosquiotoes venom for anti malaria and other pathogen agents also have been formulated to avenge those diseases. Sustainable manufacturing: The manufacturing industry has started adapting the systematic approach for the biomimicry method in their various processes in a very serious and efficient attempted manner for more eco friendly product designs. The products are designed with keeping in mind the EES ( economic, environment and social ) which often led to reflect each other ; bio mimicry helps to balance these three factors and asses different products at a very early stage.The study of morphology of various surfaces leading to the slection of materials is mimicked from that of the relavant application. Example: The surface of Tio2 is sprayed with PEEDOS:PSS for the production of Solar cells which was adopted from Plants. The Process of Photosynthesis.The main agenda for this field is to take the help of Compter Aided Engineering and the Data to give sustainable and function efficient products at a very large scale at minimal cost of production. Architecture: The basic concept of architecture came from mimicking the trees withstanding extreme climate and different microorganisms including the ant mounds ; the spiders web. We generally think of termites as destroying buildings, not helping design them. The modern buildings have an internal climate control system originally inspired by the termite mounds. The operation of buildings represents 40% of all the energy used manually so more energy efficient concepts have to be introduced. The Honey comb structure morphology has been motivated for the selection of building materials which can withstand high pressure winds and climate conditions. The tensile strength of spiders larva directs to the materials of large scale structures requiring greater tension forces. Gecko (Adhesion applications ): Geckos have the amazing gift the adhere and repel their feet and toes on the surface making them stick to the surface to and fro quickly.It is possible for them to perform such a task because of millions of nano-scale hairs present on their toes known as setae and spatulae. This creates friction between the toe and the surface area on which the toe is adhered to and as the surface area increases the frictional force on the toa and the surface also increases. We can note the presence of Vander Wals forces in between the toe and the surface, Vanderwalls Forces are fragile attractive forces usually present between nearly all chemicals and materials. The frictional force requires the application of pressure for adhesion and load removal for the to and fro movement ; The Nanotechnology steps into the operation where various topographical and morphological scaling techniques are graded and used to itch down the patterns down to the nanoscale and make them im plement on the industrial scale products. The ability that the gecko adapts to create such high amount of adhesion reasons to the hierarchical and fibrillar structure on its feet. The High surface area usage of the spatula at each step enables gecko to increase the toe-pad surface area and features to use them in a combinationWith the aid of the multitiered porous anodic alumina template and capillary force bridged nanoimprinting, we can successfully plant a gecko imprint toe pad formation of nanopillars.Improvisation has also been done to increase the adhesitivity of the application to upto 150%. As the surface area gradually decreased the adhesive forces also emulated. The pillar topography also aided the fact of the increase in hydrophobicity, which proved to be quite fruitful in the applications of dry cleaning materials and super hydrophobic applications. Super-Hydrophobic Surfaces: The basic example of a naturally hydrophobic surface is the lotus leaf, the leafs when scaled down to a Nano size ; it is observed to have the surface with repels the water particles on its surface. This tendency allows the plant to withstand the dirt and self-cleaning mechanism. When the leaf is encountered with water, it creates thee superhydrophobic angle at around 160 ° which allows the water to roll down the leaf on the way helping to coolect all the dirt patricles on its surface. This is known as the lotus effect where the surface structure is at micrometer-scale bumps as well as nanometer-scale hairlike structures with a layer of wax on the leaves. The leaf air composite structure allows the air to trap beneath the water droplets and is the main reason for high contact angle and rolling behaviour of water droplet on the leaf. With the help of nanofabrication methods a superhydrophobic and transparent biomimetic surface can be fabricated by us ing the colloidal lithography and plasma etching combination. Plasma etching techniques are also advanced enough to built tall tower like strucutres on glass sheets and adding to that coating with fluoroalkylsilane self-assembled monolayers in the aim to obtain the chemical layers with a low surface energy, the contact angle of the nanostructured surface around 150 ° and 110 ° for water and hexadecane, respectively. In addition to the super hydrophobic abilities they also retained the quality of transparency which also adds on the property and creates a massive impact in the solar cell industry. sd Solar Cells: The butterfly wing scales templating method is easy and economic design for the synthesis of hierarchically periodic microstructure titania photoanode without the need for complicated experimental conditions or equipments, such as photo lithography adopted. The quasihoneycomb structure titania replica photoanode has a perfect light absorptivity and higher surface area, which give great advantages to the light harvesting efficiency and dye sorption. This structure gives the butterfly ultrablackness wings, so it is convincing that we could obtain potential ultra-absorptivity photoanode adopting the quasi-honeycomb structure. This method also gives us a better option for photothermal, photocatalyzed, and photosensitized devices research. This fabrication method have the chances for their application on other chitin substrate template and metal oxide systems that could turn out to be in the production of optical, magnetic. or electric devices or components as building blocks for nanoelectronic, magnetic, or photonic integrated systems The butterfly wing have a greater band of reflectance for the Uv rays because of the alternative layers of Air and chitin. The honeycomb structure has the upper hand of refracting on trapping light similar to the fiberoptic cable. The relative high refractive index on the wings helps to entrap the solar rays much easily. That is, the light enters the material, but whenever it co inciceds with the rest of the surface it is mirrored back to that of the reflective part. This shows that no incident light is wasted everything is reflected back and used. Nanotechnology plays its part in managing the topography and aiding the need to study the reflections and increasing optical path length than the wings. Nanofabrication aids to the butterfly wing scales microstructure titania film photoanode and can improve the wing scales and light absorbitivity on a particular surface area of the DSC photoanode. References: Huh, D., Torisawa, Y., Hamilton, G., Kim, H. and Ingber, D. (2012). Microengineered physiological biomimicry: Organs-on-Chips. Lab on a Chip, 12(12), p.2156. Alexandridis, G., Tzetzis, D. and Kyratsis, P. (2016). Biomimicry in Product Design through Materials Selection and Computer Aided Engineering. IOP Conference Series: Materials Science and Engineering, 161, p.012046. Nesta.org.uk. (2017). Biomimicry | Nesta. [online] Available at: http://www.nesta.org.uk/event/biomimicry Wootton-Beard, P., Xing, Y., Durai Prabhakaran, R., Robson, P., Bosch, M., Thornton, J., Ormondroyd, G., Jones, P. and Donnison, I. (2016). Review: Improving the Impact of Plant Science on Urban Planning and Design. Buildings, 6(4), p.48. Arndt, D. (2017). Natures nanotechnology, bio-mimicry, and making the superpowers of your dreams a reality. [online] Sustainable Nano. Available at: http://sustainable-nano.com/2013/12/03/natures-nanotechnology-bio-mimicry-and-making-the-superpowers-of-your-dreams-a-reality-4/ Hu, S. and Xia, Z. (2012). Rational Design and Nanofabrication of Gecko-Inspired Fibrillar Adhesives. Small, 8(16), pp.2464-2468. Aryal, M., Ko, D., Tumbleston, J., Gadisa, A., Samulski, E. and Lopez, R. (2012). Large area nanofabrication of butterfly wings three dimensional ultrastructures. Journal of Vacuum Science Technology B, Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena, 30(6), p.061802. Ho, A., Yeo, L., Lam, Y. and RodriÃÅ' guez, I. (2011). Fabrication and Analysis of Gecko-Inspired Hierarchical Polymer Nanosetae. ACS Nano, 5(3), pp.1897-1906. Lim, H., Jung, D., Noh, J., Choi, G. and Kim, W. (2009). Simple nanofabrication of a superhydrophobic and transparent biomimetic surface. Science Bulletin, 54(19), pp.3613-3616. Zhang, B., Park, J., Kim, K. and Yoon, H. (2012). Biologically inspired tunable hydrophilic/hydrophobic surfaces: a copper oxide self-assembly multitier approach. Bioinspiration Biomimetics, 7(3), p.036011. Ensikat, H., Ditsche-Kuru, P., Neinhuis, C. and Barthlott, W. (2011). Superhydrophobicity in perfection: the outstanding properties of the lotus leaf. Beilstein Journal of Nanotechnology, 2, pp.152-161. Zhang, W., Zhang, D., Fan, T., Gu, J., Ding, J., Wang, H., Guo, Q. and Ogawa, H. (2009). Novel Photoanode Structure Templated from Butterfly Wing Scales. Chemistry of Materials, 21(1), pp.33-40. Sharklet.com. (2017). Technology Overview | Sharklet Technologies, Inc.. [online] Available at: http://sharklet.com/our-technology/technology-overview/

Community Health Nursing Essay

The implementation of a program which makes health care accessible is a goal of any society. In line with this goal, the establishment of community health nursing was formed. This provided better opportunities for people to acquire the right health care assistance for each of their concerns. There were some factors that may be attributed in the formation of a health nursing. These influenced the creation of the program which intended to provide resolutions for problems that have long been encountered. The first source of influence may be justified even before the 19th century Europe. In the past, family members who were sick were just attended by female members of the family and were not able to access full health care from a professional or a specialist (Allender, 2004). One of the great problems which were encountered by societies was the minimal opportunity for ordinary people to go to a medical specialist. Almost always the case, only those who have the economic capability were able to avail these types of services. Add to that the seemingly underdeveloped infrastructures back then. This paved the way for an idea to bring at least satellite health care units in small communities to service the general public. One more attribute which lead to the development of community health care can be pointed out to religious charities. The monks in Florence, Italy had committed a historical health care service for those who encountered accidents. They even provided first aid solutions for people who needed their help even on a 24 hour basis. As a matter of fact, these religious figures even provided the necessary health care for various pilgrims to some of the considered holy lands based on religious beliefs. During the medieval times, there have also been great developments in community based health services. There was a time when a law catering to the poor of England was passed in 1601. This rule designated the instructions for health specialists to render their services to the poor who did not have any means of availing health care. Since the governing sector is centralized in the royal institution, it was really easy to disseminate the services to identifiable poor communities in the country. Another historic event took place in France when the Friendly Visitor Volunteers was formed. In 17th century France, there was a great deal in re-establishing the economy. This prompted the organization to render public health services by sending the service directly to the homes of the poor and disabled. The main funding process of the organization was initiated by wealthy women individuals of the society who cared for the welfare of the general public. The community health nursing was definitely a very good approach in caring for the needy and unfortunate. However, by the time the Industrial Revolution hit Europe and America, the group of these community based health units were greatly reduced. This paved the way for what the present health care structure societies have today. Hospitals and health centers were established even in bigger units and concentrated near urban areas. This was in direct contrast to the former approach of delegating specific health units among communities. Even though the extent of community health nursing is already reduced, newer counterparts in modern society today still has the same principle. Home nursing can be availed today via appointments with doctors and nurses. There are also some programs among today’s hospitals which can provide an extended health care service at home based on agreements. Moreover, the establishment of home care nursing centers provides at least a refuge for patients outside of hospitals. The modern day health professionals are partnering directly with individuals who want to improve their communities in promoting optimum health care (Richmond Health, 2001).

John Dewey on Education Essay

John Dewey, Mortimer Adler and Nel Noddings impacted our system of education in very profound ways. Dewey believed that there should be communication between the student and the teacher. Adler believed that schools should only teach the traditional courses (English, Math, Science, Social Studies and Foreign Language). Noddings believed that teachers should be more caring towards their students. John Dewey’s idea of education greatly affected our system of education today. John Dewey’s ideas for education were to concentrate on students’ psychological and sociological qualities. Dewey believed in promoting an â€Å"unconscious education† where â€Å"the individual gradually comes to share in the intellectual and moral resources which humanity has succeeded in getting together. He becomes an inheritor of the funded capital of civilization† (Dewey 261). In other words, he thought this was a good method for teachers to analyze a student’s behavior in order to teach them more effectively. This also provided an opportunity for the student to learn without even realizing it. Dewey stated that a student’s psychological needs were the basis of his method of education. The child’s own instinct and powers furnish the material and give the starting-point for all education† (Dewey 262). Dewey stressed the idea that, â€Å"Without insight into the psychological structure and activities of the individual the educative process will†¦be haphazard and arbitrary† (Dewey 262). Dewey was also extremely interested in the social aspects of a student. He said that the, â€Å"knowledge of social conditions, of the present state of civilization, is necessary in order to properly interpret the child’s powers† (Dewey 262). This was a new technique for an educator to see and distinguish the instincts and tendencies in a student. Therefore, in order for an educator to know more about a student he/she must first study the student’s psychological traits in order to understand the unique characteristics of a child’s capacities, interests and habits. Then the teacher must translate their findings into terms of what they believe the child is capable of in a social setting. In my opinion, Dewey showed a balance between the dialectic of academics and affective goals. This is also known as transaction, which is having both the teacher and the student interact in the classroom. Dewey believed that the academic goals of education should be, â€Å"a process of living and not a preparation for future living† (Dewey 263). He stated that the teachers’ job is not to influence him but to help guide the student into successfully forming with the community by letting the student experience some life occurrences. â€Å"The teacher is not in the school to impose certain ideas or to form certain habits in the child, but is there as a member of the community to select the influences which shall affect the child† (Dewey 263 – 264). Dewey also believed that tests should only be used to examine a child’s social capabilities in the real world. â€Å"Examinations are of use only so far as they test the child’s fitness for social life and reveal the place in which he can be of the most service and where he can receive the most help† (Dewey 264). In my opinion, this would be more of a conceptual test where the child can voice his or her own opinions. Dewey’s main affective goals were to deepen the child’s meaning of himself and his values. It is the business of the school to deepen and extend his sense of the values bound up in his home life† (Dewey 263). Dewey believed that it was important for the school to implement lessons that related to what a child would do at home. The school would also be responsible for simplifying their social life because; â€Å"existing life is so complex that the child cannot be brought into contact with it without either confusion or distraction† (Dewey 263). Therefore, if the child is exposed to too much social stimulation he will become, â€Å"either unduly specialized or else disintegrated† (Dewey 263). I believe that Dewey’s views show that he is against standardization in schools. He believed that there was a lack of conscious states in schools. He asserts that children are, â€Å"thrown into a passive, receptive, or absorbing attitude† (Dewey 265). Dewey’s viewpoint is still an active discussion topic in today’s education system. However, some school districts insist on rote learning because their schools receive more funding when there is a high percentage of passing students on standardized tests. According to Linda McNeil, students are taught on how to pass these tests without really learning. For example, McNeil states that, â€Å"students report that in the drills on the TAAS reading section, they frequently mark answers without reading the sample text. They merely match key words in an answer choice with key words in the text† (McNeil 218). According to Dewey, this is â€Å"not permitted [in following] the law of nature† (Dewey 265), resulting in â€Å"friction and waste† (Dewey 265). Dewey believed that proper instruction should be exemplified by, â€Å"the preparation and presentation of lessons [which] might be more wisely and profitably expended in training the child’s power of imagery and in seeing to it that he was continually forming definite, vivid, and growing images of the various subjects with which he comes in contact in his experience† (Dewey 266). Standardization is not they key component of education, even though the state and federal government believe this is an important element for success. According to Gerald Bracey, when students are applying to college, the SAT exam should be used as a guideline and not the final decision in acceptance. Bracey stated that the, â€Å"SAT scores had been falling for fourteen years† (Bracey 47). He also stated that, â€Å"While the developers of the SAT still called their test a ‘mere supplement,’ the public now saw it as the platinum rod for measuring school performance. And that performance was getting worse† (Bracey 47). Somehow over time, a student’s SAT score developed into an extremely significant number which seemed to become the overall determination of a student’s intelligent. It seems harsh and unbalanced to put so much emphasis on one test. Of course, applicants are told that in combination with their SAT scores; their grades and outside activities are taken into consideration for college admittance. But the truth is these SAT scores still remain a huge factor for college applicants. Studies have shown that a high SAT score does not guarantee high grades in college however the politics behind these tests are stronger than the public’s opinion in order to get these tests repealed. Standardized tests do not lead the student to come into contact with the subject at hand or the experience related to it. They also do not show the overall picture of an individual or what he or she can contribute while attending college. Scott Thompson is against the test-based reform of today’s society. Thompson claims that, â€Å"The human hearts and minds of others, I believe, are simply too complex and too inaccessible to read as a book† (Thompson 160). Thompson argues that the differences between test-based reform and standards-based reform. He concluded that standards-based reform involves more cooperation from parents, teachers and the students. It also gives the students a high-quality method of learning and not simply learning techniques for test taking. â€Å"We should be interested in students who can produce high quality work rather than students who have mastered the ability to take standardized tests† (Thompson 159). Thompson would love to see that the idea of standardized tests be abandoned in the future. Thompson argues that by giving these students standardized tests that they are reducing their potential of demonstrating their intellect, social and personal sides to the community. Test-based reform, through its focus on high-stakes test, narrows the curriculum to what is included on the tests and reduces instructional practice to test preparation† (Thompson 159). In contrast, â€Å"standards-based reform†¦involves a complete abandonment of the bureaucratic, ‘seat time’ approach to education and replaces it with a system of learning communities dedicated to helping all students reach their intellectual, social, and personal potential† (Thompson 159). To summarize, without requiring students to take standardized tests they will greatly increase their academic potential and affective abilities. Bill Bigelow also stresses his concern of standardization. He believes that, â€Å"social studies knowledge is little more than acquiring piles of disconnected facts about the world† (Bigelow 231) and that â€Å"the world can’t be chopped into multiple choice questions, [in] that you can’t bubble in the truth with a number-two pencil† (Bigelow 239). Bigelow would be ecstatic to see the state do away with standardized tests. He demonstrates some strong educational goals that the state should follow that show a balance between academic and affective goals for education. He claims that teachers should, â€Å"construct rigorous performance standards for students that promote deep thinking about the nature of our society. These efforts should acknowledge the legitimacy of a multicultural curriculum of critical questions, complexity, multiple perspective, and social imagination. They should recognize that wisdom is more than information† (Bigelow 239). I agree with his statement. When considering the famous quote, â€Å"knowledge is power†; have we gained knowledge when we have learned the means by which to pass a standardized test? Or has knowledge been gained when a student has the sense of understanding conceptual ideas about society and civilization as a whole? I feel that standardized testing is something elected state officials want because these tests provide numbers and numbers are easy to put into a spreadsheets and show which schools are getting high scores and which schools are getting low scores. It is an easy format to determine budgets; one test is suitable for all students. It is harder to define guidelines on how or what teachers should teach conceptually because that leads to a broader spectrum of learning. In conclusion, I believe that standardized tests are the â€Å"dumbing down of America†. These tests inhibit our abilities to question and reflect. The state and federal governments do not really want the American public to get smarter. They want a simple way to control what students learn and how they learn it. While many people agree that standardization is not improving learning, we are still unable to do away with these tests due to all of the politics involved. I would love for high schools to be more like colleges in that, teachers can use whatever methods of teaching they like just as professors do. Unfortunately, this is not the case. Obviously, there are essential fundamental topics that much be taught that are necessary in order to have the basic foundation on which to grow intellectually. I feel that once a student has mastered the basics, it is crucial to one’s development to discuss controversial issues and to intelligently question the ways of the world. I agree with Bill Bigelow; I do not believe that one test is a thorough determinant of a student’s ability and mastery of various concepts. A famous quote by George Santayana states, â€Å"Those who cannot remember the past are condemned to repeat it†. With all the controversial issues and problems in the world, shouldn’t learning how to use one’s mind and think â€Å"outside the box† be considered an integral part of learning? Isn’t it important and valuable to society to be able to intelligently discuss solutions rather than just be considered smart because you aced the SAT?

The Importance Of Charting Genetic Interactions On A...

RESEARCH STRATEGY A. SIGNIFICANCE Charting genetic interactions in a mammalian cell will help us understand normal cell processes. A map of interactions will also pinpoint what goes wrong in diseases like cancer. But deciphering the genetic circuitry of the mammalian cell remains a daunting challenge. One major obstacle to annotating genetic interactions is their number. In a genome of 20,000 genes, there are 2 x 108 possible pairwise interactions. Either gene-gene or protein-protein interactions can be used to unravel molecular networks. In yeast, scientists employ synthetic genetic array analysis to map gene interactions (Costanzo et al., 2010; Tong et al., 2001; Tong et al., 2004). In Caenorhabditis elegans, they use RNA interference†¦show more content†¦But only a modest fraction of interactions are tested (Lee et al., 2004; Lee et al., 2008). Our understanding of mammalian genetic interactions is even less impressive. Large-scale efforts to map the protein interactome in humans have begun (Gandhi et al., 2006). But only about 10% of potential interactions have been evaluated (Rual et al., 2005; Venkatesan et al., 2009). Furthermore, genetic interactions in humans and mammals remain unexplored. The overlap between human, yeast, C. elegans, and fly protein interaction networks is small (Gandhi et al., 2006). Hence, it is necessary to explore mammalian genetic interactions in the mammalian setting. A problem for mammalian cells is the lack of a simple and cheap method for combining alleles of distinct genes in the same cell. Our hypothesis is that mammalian cells must thrive by exploiting combinations of genes, in fact, genetic networks that both protect the cell from destruction and enhance its survival. We believe these networks involve genes that tend to be coordinated in their copy number alterations (CNAs), even when they are located at a distance on the genome. Our recent work studying genetic networks that exist within libraries of radiation hybrid (RH) cells have elucidated key survival-enhancing interactions with remarkable specificity (Lin et al., 2010). This work identified genetic interactions with close to single gene